Journal: PLoS ONE

Article Title: Cross-Species Genome Wide Expression Analysis during Pluripotent Cell Determination in Mouse and Rat Preimplantation Embryos

doi: 10.1371/journal.pone.0047107

Figure Lengend Snippet: Fold change scatterplots. Cross species comparison of the fold change expression of the genes in the pathway “Development, Notch Signaling Pathway” from GeneGo. In green are marked the genes for which fold change differ in mouse and rat within the three comparisons: Blastocyst versus (vs) Morula, ICM versus Blastocyst, and ICM versus Morula. In red are marked those genes that have a similar fold change pattern in the two species in each comparison. With a special marker there are highlighted 6 selected genes that have differential expression patterns in the two species. The complete list of all the genes analyzed with their fold changes is reported in . B. Expression signal profile plots. Expression level of 6 selected genes from the Notch pathway. In blue are marked the expression levels of the genes in the mouse and in red the one in the rat embryos. MO: Morula, ICM: Inner cell mass, BL: Blastocyst. The unit is log2 of measured expression.

Article Snippet: We analyzed 27 genes present in the pathway “Development Notch Signaling Pathway” in GeneGo.

Techniques: Comparison, Expressing, Marker, Quantitative Proteomics

Journal: PLoS ONE

Article Title: Cross-Species Genome Wide Expression Analysis during Pluripotent Cell Determination in Mouse and Rat Preimplantation Embryos

doi: 10.1371/journal.pone.0047107

Figure Lengend Snippet: A. The BMP protein family. Scatterplots of the fold changes measured in the three comparisons for 9 members of the BMP protein family in the mouse and in the rat. The complete list of all the genes analyzed as well as their fold changes are reported in . B–C. Same analysis like for the BMP proteins was performed for 4 members of the BMP receptor family ( B. ) and for 6 members of the SMAD protein family ( C. ). D. Fold change scatterplots. Cross species comparison of the fold changes expression of the genes in the pathway “Development, BMP signaling” from GeneGo (see also ). The data were analyzed as described in . E. Expression signal profile plots. Expression level analysis of 4 selected genes from the BMP pathway. Mouse: blue; Rat: red; MO: Morula; ICM: Inner cell mass; BL: Blastocyst. The unit is log2 of measured expression.

Article Snippet: We analyzed 27 genes present in the pathway “Development Notch Signaling Pathway” in GeneGo.

Techniques: Comparison, Expressing

Journal: PLoS ONE

Article Title: Cross-Species Genome Wide Expression Analysis during Pluripotent Cell Determination in Mouse and Rat Preimplantation Embryos

doi: 10.1371/journal.pone.0047107

Figure Lengend Snippet: A–B. Scatterplots of the fold changes measured in the three comparisons for 21 members of the FGF factor family ( A. ) and for 7 FGF receptors ( B. ) in the mouse and in the rat. The complete list of all the genes analyzed as well as their fold changes are reported in . C. Fold change scatterplots. Cross species comparison of the fold changes expression of the genes in the pathway “Development, FGFR signaling pathway” from GeneGo (see also ). The data were analyzed as described in . D. Expression signal profile plots. Expression level analysis of 5 selected genes from the FGFR pathway. Mouse: blue; Rat: red; MO: Morula; ICM: Inner cell mass; BL: Blastocyst. The unit is log2 of measured expression.

Article Snippet: We analyzed 27 genes present in the pathway “Development Notch Signaling Pathway” in GeneGo.

Techniques: Comparison, Expressing

Journal: Molecular & Cellular Proteomics : MCP

Article Title: Proteome Analysis of Plasmodium falciparum Extracellular Secretory Antigens at Asexual Blood Stages Reveals a Cohort of Proteins with Possible Roles in Immune Modulation and Signaling *

doi: 10.1074/mcp.M900029-MCP200

Figure Lengend Snippet: Microarray experiments and analyses to detect change in expression of genes involved in Notch signaling in mice. Total RNA was enriched from splenocytes from primed mice following stimulation with PfSEL1, PfSEL2, and medium only (control) for 24 h. 1 μg of RNA was processed for microarray analyses using the GEArray Mouse Notch Signaling Pathway Gene array from SuperArray strictly following the manufacturer's instructions. The table depicts genes that are predominantly down-/up-regulated, their description and position on the arrays, and the log2 (-fold ratio) values representing the change in expression of these genes following the two stimulations (with respect to control). LIM, Lin11, IsI-1 and Mec-3 proteins; FBJ, Finkel-Biskis-Jinkins.

Article Snippet: Total RNA was enriched from splenocytes from primed mice following stimulation with PfSEL1, PfSEL2, and medium only (control) for 24 h. 1 μg of RNA was processed for microarray analyses using the GEArray Mouse Notch Signaling Pathway Gene array from SuperArray strictly following the manufacturer's instructions.

Techniques: Microarray, Expressing, Control